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发布日期:2023-02-23
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梁箫 副教授


梁箫,女,满族,19832月生,辽宁大连人。博士,副教授、硕士生导师。水生生物系专任教师。兼任中国海洋湖沼学会养殖生态学分会副秘书长、国家现代海洋牧场科技创新联盟专家委员会委员,学术期刊Frontiers in Marine Science客座主编。

 

教育背景

20123月毕业于日本长崎大学生产科学研究科海洋生产科学专业,获博士学位。

20093月毕业于日本长崎大学生产科学研究科水产学专业,获硕士学位。

2006年毕业于大连海洋大学水产养殖专业,获学士学位。

 

教学工作情况

本科生课程:贝类学、贝类增养殖学、蛋白质组学、微生物生态学;

研究生课程:污损生物学、贝类人工繁育、酶与蛋白质、高级水生生物学(博士)。

 

主要研究方向

海洋细菌胞外蛋白在贻贝发育中的作用研究;

受体调控贻贝附着的分子机制研究;

环境变化对贝类生长发育分子机制研究;

海洋生物活性物质的开发与应用研究。

 

主持和参与的科教项目

[1] 国家重点研发计划“战略性科技创新合作”重点专项项目,中国-葡萄牙星海“一带一路”联合实验室建设与联合研究,2022.11-2025.10,承担任务

[2] 上海市科委高端外国专家项目,厚壳贻贝对海洋生物被膜附着响应的机制研究,2022.01-2022.12,主持

[3] 国家自然科学基金青年项目,厚壳贻贝肾上腺素能受体和5-羟色胺受体调控幼虫变态的分子机理研究,2017.01-2019.12,主持

[4] 上海市青年优秀学术带头人计划,厚壳贻贝幼虫附着变态发育的分子机理研究,2020.10.1-2023.9.30,参与

[5] 浙江省舟山市嵊泗县枸杞乡人民政府枸杞岛海域贻贝养殖的种质、环境及养殖策略研究课题,2019.6-2021.5,参与

[6] 国家重点研发计划政府间国际科技创新合作重点专项,通过比较基因组学方法解析贻贝属免疫组库,2017.04-2019.03,参与

[7] 国家自然科学基金面上项目,厚壳贻贝稚贝附着机理研究,2015.01- 2018.12,参与

[8] 上海市科委重点基础项目,东:S蛭甯鲋饕妇嗳旱母阶庞肟刂萍际,2012.09-2015.06,参与

 

发表的主要论文情况(近五年)

[1] He CH, Zhang W, Hu XM, Asami Yoshida, Kiyoshi Osatomi, Liang X*, Yang JL*. 2023. Larval settlement and metamorphosis of Mytilus coruscus in response to varying bacterial capsular polysaccharide. Frontiers in Marine Science. 10:95. (IF: 5.247,5-yr IF: 5.72) Q1 

[2] Zhu YT, Liang LL, Liu TT, Liang X, Yang JL*. 2023. Effects of L-Arginine on Nitric Oxide Synthesis and Larval Metamorphosis of Mytilus coruscus. Genes, 14(2), 450. (IF: 4.141,5-yr IF: 4.474) Q2

[3] Zhang W, Wang YY, Hu XM, Zhou ZS, Zhu, YT, Liang X, Yang JL*. 2022. AMPK Promotes Larval Metamorphosis of Mytilus coruscus. Genes. 13 (12), 2384. (IF: 4.141,5-yr IF: 4.474) Q2

[4] Wang M, Xia J, Jawad M, Wei WB, Gui L, Liang X, Yang JL, Li MY*. 2022. Transcriptome sequencing analysis of sex-related genes and miRNAs in the gonads of Mytilus coruscus. Frontiers in Marine Science. 9:1013857. (IF: 5.247,5-yr IF: 5.72) Q1

[5] Li JZ, Zhang C, Hu XM, Asami Y, Kiyoshi O,Guo XP, Yang JL, Liang X. 2022. Impact of diferent enzymes on bioflm formation and mussel settlement. Scientific Reports. 2022, 12: 4685. (IF: 4.997,5-yr IF: 5.516) Q2

[6] Tan JY, Liang X, Yanv JL, Zhou SX*. 2022. Sol–gel-derived hard coatings from tetraethoxysilane and organoalkoxysilanes bearing zwitterionic and isothiazolinone groups and their antifouling behaviors. Journal of Materials Chemistry B. 10(3): 406-417. (IF: 7.571, 5-yr IF: 6.788) Q1

[7] Liang X, Zhang JB, Shao AQ, Hu XM, Wan R*, Yang JL*. 2021. Bacterial cellulose synthesis gene regulates cellular c-di-GMP that control Biofilm formation and mussel larval settlement. International Biodeterioration & Biodegratation. 165:105330. (IF: 4.907, 5-yr IF: 5.354) Q2

[8] Hu XM, Zhang JB, Ding WY, Liang X, Wan R, Dobretsov S. Yang JL*. 2021. Reduction of mussel metamorphosis by inactivation of the bacterial thioesterase gene via alteration of the fatty acid composition. Biofouling. 37(8): 911-921. (IF: 3.797, 5-yr IF: 3.944) Q2

[9] Li YF*, Wang YQ, Zheng Y, Shi X, Wang C, Cheng YL, Zhu X, Yang JL, Liang X*. 2021. Larval metamorphosis is inhibited by methimazole and propylthiouracil that reveals possible hormonal action in the mussel Mytilus coruscus. Scientific Reports, 11(1):19288. (IF: 4.997, 5-yr IF: 5.516) Q2

[10] Chang RH, Feng DD, Peng LH, Zhu YT, Liang X*, Yang JL. 2021. Complete genome sequence of Shewanella marisflavi ECSMB14101, a red pigment synthesizing bacterium isolated from the East China Sea. Marine Genomic. 58, 100846. (IF: 2.143, 5-yr IF=2.218) Q4

[11] Yang JL*, Feng DD, Liu J, Xu JK, Chen K, Li YF, Zhu YT, Liang X, Lu Y*. 2021. Chromosome-level genome assembly of the hard-shelled mussel Mytilus coruscus, a widely distributed species from the temperate areas of East Asia. Giga Science, 10(4): giab024. (IF: 7.658, 5-yr IF: 8.439) Q1

[12] Chang RH, Yang LT, Luo M, Yihan Fang Y, Peng LH, Yuli Wei Y, Fang J, Yang JL*, Liang X*. 2021. Deep?sea bacteria trigger settlement and metamorphosis of the mussel Mytilus coruscus larvae. Scientific Reports. 11(1): 919. (IF: 4.997,5-yr IF: 5.516) Q2

[13] Li YF, Yang XY, Cheng ZY, Wang LY, Wang WX, Liang X, Yang JL*. 2020. Near-future levels of ocean temperature weaken the byssus production and performance of the mussel Mytilus coruscus. Science of the Total Environment. 733:139347. (IF:10.754, 5-yr IF: 10.237) Q1

[14] Li YF, Zhu X, Cheng ZY, Liang X, Zhu YT, Feng DD, Dobretsov S, Yang JL*. 2020. 2(5H)-Furanone disrupts bacterial biofilm formation and indirectly reduces the settlement of plantigrades of the mussel Mytilus coruscus. Frontiers in Marine Science. 7:564075. (IF:5.247, 5-yr IF: 5.72) Q1

[15] Peng LH, Liang X, Chang RH, Mu JY, Chen HE, Yoshida A, Osatomi K, Yang JL*. 2020. A bacterial polysaccharide biosynthesis-related gene inversely regulates larval settlement and metamorphosis of Mytilus coruscus. Biofouling. 36(7): 753-765. (IF:3.797, 5-yr IF: 3.944) Q2

[16] Zhu YT, Zhang Y, Liu YZ, Li YF, Yoshida A, Osatomi K, Yang JL*, Liang X*. 2020. Nitric oxide negatively regulates larval metamorphosis in hard-shelled mussel (Mytilus coruscus). Frontiers in Marine Science. 7:356. (IF:5.247, 5-yr IF: 5.72) Q1

[17] Liang X, Zhang XK, Peng LH, Zhu YT, Yoshida A, Osatomi K, Yang JL*. 2020. The flagellar gene regulates biofilm formation and mussel larval settlement and metamorphosis. International Journal of Molecular Sciences. 21(3):710. (IF:6.608, 5-yr IF: 6.628) Q1

[18] Peng LH, Liang X, Xu JK, Dobretsov S, Yang JL*. 2020. Monospecific biofilms of Pseudoalteromonas promote larval settlement and metamorphosis of Mytilus coruscus. Scientific Reports. 10(1):2577. (IF: 4.997, 5-yr IF: 5.516) Q2

[19] Li YF, Cheng YL, Chen K, Cheng ZY, Zhu X, Cardoso JCR, Liang X, Zhu YT, Power DM, Yang JL*. 2020. Thyroid hormone receptor: A new player in epinephrine-induced larval metamorphosis of the hard-shelled mussel. General and Comparative Endocrinology 287:113347. (IF:3.225, 5-yr IF: 3) Q3

[20] Li YF, Chen YW, Xu JK, Ding WY, Shao AQ, Zhu YT, Wang C, Liang X*, Yang JL*. 2019. Temperature elevation and Vibrio cyclitrophicus infection reduce the diversity of haemolymph microbiome of the mussel Mytilus coruscus. Scientific Reports. 9: 16391. (IF: 4.997, 5-yr IF: 5.516) Q2

[21] Liang X, Wang JL, Liu YZ, Peng LH, Li YF, Batista FM, Power DM, Gui L*, Yang JL*, 2019. Complete genome of a marine bacterium Vibrio chagasii ECSMB14107 with the ability to infect mussels. Marine Genomics. 48: 48-51. (IF: 2.143, 5-yr IF=2.218) Q4

[22] Li YF, Xu JK, Chen YW, Ding WY, Shao AQ, Liang X, Zhu YT, Yang JL*. 2019. Characterization of gut microbiome in the mussel Mytilus galloprovincialis in response to thermal stress. Frontiers In Physiology. 10:1086. (IF: 4.755, 5-yr IF: 5.316) Q1

[23] Wang JS, Peng LH, Guo XP, Yoshida A, Osatomi K, YF Li, Yang JL*, Liang X*. 2019. Complete genome of Pseudoalteromonas atlantica ECSMB14104, a Gammaproteobacterium inducing mussel settlement. Marine Genomics. 46:54-57. (IF: 2.143, 5-yr IF=2.218) Q4

[24] Liang X, Chen K, Li YF, Bao WY, Yoshida A, Osatomi K, Yang JL*. 2019. An ɑ2-adrenergic receptor is involved in larval metamorphosis in the mussel, Mytilus coruscus. Biofouling. 35: 986-996. (IF: 3.797,5-yr IF: 3.944) Q2

[25] Li YF, Liu YZ, Chen YW, Chen K, Batista FM, Cardoso JCR, Chen YR, Peng LH, Zhang Y, Zhu YT, Liang X, Power DM, Yang JL*. 2019. Two toll-like receptors identified in the mantle of Mytilus coruscus are abundant in haemocytes. Fish & Shellfish Immunology. 90:134-140. (IF: 4.622, 5-yr IF: 4.799) Q3

[26] Liang X, Peng LH, Zhang S, Zhou SX, Yoshida A, Osatomi K, Bellou N, Guo XP*, Dobretsov S, Yang JL*. 2019. Polyurethane, epoxy resin and polydimethylsiloxane altered biofilm formation and mussel settlement. Chemosphere. 218: 599-608. (IF: 8.943, 5-yr IF: 8.52) Q1

[27] Peng LH, Liang X, Guo XP, Yoshida A, Osatomi K, Yang JL*. 2018. Complete genome of Pseudoalteromonas marina ECSMB14103, a mussel settlement-inducing bacterium isolated from the East China Sea. Marine Genomics. 41:46-49. (IF: 2.143, 5-yr IF=2.218) Q4

[28] Li YF, Yang N, Liang X, Yoshida A, Osatomi K, Power D, Batista FM, Yang JL*. 2018. Elevated seawater temperatures decrease microbial diversity in the gut of Mytilus coruscus. Frontiers In Physiology. 9:839. (IF: 4.755, 5-yr IF: 5.316) Q1

[29] Liang X, Chen YR, Gao W, Guo XP, Ding DW, Yoshida A, Osatomi K, Yang JL*. 2018. Effects on larval metamorphosis in the mussel Mytilus coruscus of compounds that at on downstream effectors of G-protein-coupled receptors. Journal of The Marine Biological Association of the United Kingdom. 98(2), 333–339. (IF:1.559, 5-yr IF: 1.697) Q3

[30] 牟嘉仪,胡晓梦,彭莉华,竹攸。梁箫,杨金龙. 细菌运动性对生物被膜的动态演替及其对厚壳贻贝附着的影响. 渔业科学进展, 2022

[31] 邵安琪,李嘉政,张俊波,万荣,杨金龙,梁箫. 纤维素对Pseudoalteromonas marina生物被膜生物学特性及厚壳贻贝幼虫附着变态的影响. 水产学报, 2022

[32] 张驰,王劲松,杨金龙,张俊波,万荣,梁箫*. 海假交替单胞菌(Pseudoalteromonas marina)pilZ基因缺失抑制厚壳贻贝附着变态. 海洋学报, 2022, 44(4): 95–103.

[33] 刘志显,李嘉政,梁邻利,冯丹丹,梁箫,杨金龙,竹攸汀*. 厚壳贻贝(Mytilus coruscus)McCaspase 3-4基因的克隆及其在幼虫变态中的作用. 水生生物学报, 2022, 46(08): 1168-1176.

[34] 陈慧娥,贺康,贺楚晗,竹攸。罱鹆,梁箫*. 藻酸盐对海假交替单胞菌生物被膜形成及厚壳贻贝附着变态的影响. 大连海洋大学学报, 2022, 37(04): 620-626.

[35] 王林雨,史雪,杨跃明,王雨晴,梁箫,杨金龙,李一峰*. GABA受体拮抗剂荷包牡丹碱和CGP52432对厚壳贻贝幼虫附着变态的影响. 水产学报, 2022, 46(06): 942-949.

[36] 蔡雨珊,任泓妤,竹攸。罱鹆,张俊波,万荣,梁箫*. 海假交替单胞菌fliC-02330基因缺失影响生物被膜形成及厚壳贻贝幼虫附着变态. 微生物学通报, 2021, 49(03): 899-910.

[37] 吴静娴,李嘉政,胡晓梦,丁文扬,杨金龙,梁箫* 脂多糖对细菌生物被膜形成及厚壳贻贝幼虫变态的影响. 水产学报, 2021, 46(11): 2134-2142.

[38] 徐嘉康, 王劲松,方怡涵,杨金龙,梁箫*. 厚壳贻贝肠道细菌的生物被膜对其幼虫和稚贝附着的影响. 海洋学报, 2021, 43(9): 81–91.

[39] 蔡雨珊,张秀坤,竹攸。罱鹆,梁箫*. 海假交替单胞菌(Pseudoalteromonas marina)鞭毛蛋白对生物被膜形成及厚壳贻贝附着的影响. 海洋学报, 2021, 43(4): 75–83.

[40] 梁箫,丁文扬,张弛,蔡雨珊,杨金龙* 3 种脂肪酸对生物被膜形成及厚壳贻贝幼虫附着变态的影响. 大连海洋大学学报, 2021, 36(4): 580-586.

[41] 杨金龙, 段志鸿, 丁文扬, 徐嘉康, 顾忠旗, 梁箫*. 维生素B7 B12 对细菌生物被膜形成及厚壳贻贝幼虫变态的影响. 渔业科学进展, 2021, 42(5): 113–123.

[42] 常睿珩,许康豪,蔡雨珊,杨金龙,梁箫*. 钙离子对海假交替单胞菌生物被膜形成及厚壳贻贝附着的影响.大连海洋大学学报, 2020,35(6): 893-900.

[43] 梁箫, 杨丽婷, 彭莉华, 魏玉利, 方家松, 杨金龙*. 不同温度下形成的深海菌膜对厚壳贻贝幼虫变态的影响. 水产学报, 2020, 44(10): 1728?1741.

[44] 梁箫, 童欢, 彭莉华, 杨丽婷, 常睿珩, 杨金龙*. 纤维素对海洋细菌生物被膜形成及厚壳贻贝幼虫附着变态的调控. 大连海洋大学学报, 2020, 1: 75-82.

[45] 梁箫, 刘红雨, 杨丽婷, 常睿珩, 彭莉华, 李一峰, 杨金龙*. 弧菌生物被膜的动态演替对厚壳贻贝附着的影响. 水产学报, 2020, 44(1): 118?129.

[46] 梁箫, 刘钰珠, 陈珂, 李一峰, 杨金龙*. 厚壳贻贝MyD88-4基因的生物学特性及其对沙氏弧菌的免疫应答. 水产学报, 2019, 43(11):1910-1921.

[47] 梁箫,陈珂,陈艳文,刘钰珠,李一峰,杨金龙*. 厚壳贻贝5-羟色胺2A受体(5-HT2AR)基因克隆和时空表达. 水产学报, 2018, 4212):1845-1855.

[48] 梁箫,张亚,刘钰珠,李一峰,Batista M. Frederico,Power Deborah,杨金龙*. 灿烂弧菌对厚壳贻贝免疫指标和消化酶活性的影响. 水产学报, 2018, 429):1438-1445.

 

申请和授权专利情况

[1] 梁箫,彭莉华,张秀坤,魏玉利,方家松,杨金龙. 一种深海盐单胞菌及其在诱导厚壳贻贝稚贝附着中的应用.授权国家发明专利号ZL201810315970.9

[2] 杨金龙,郭行磐,陈芋如,梁箫. 一株海洋希瓦氏细菌及其在诱导厚壳贻贝稚贝附着方面的应用. (授权国家发明专利号:ZL201410741373.4

[3] 杨金龙,李一峰,郭行磐,梁箫,李家乐. 碱性蛋白酶与聚二甲基硅氧烷的复合物及其制备方法和应用.(授权国家发明专利号:ZL201710318066.9

[4] 杨金龙,梁箫,彭莉华,陈珂,魏玉利,方家松. 一种深海芽孢杆菌及其在诱导厚壳贻贝稚贝附着中的应用.(授权国家发明专利号ZL201810423184.0

[5] 杨金龙,彭莉华,杨丽婷,魏玉利,方家松,梁箫. 一种海洋除烃海杆细菌及其在诱导厚壳贻贝稚贝附着中的应用.授权国家发明专利号ZL201810316697.1

科教工作获奖情况

[1] 2022年上:Q罂蒲Ъ际踅币坏冉保ㄅ琶谖澹

[2] 2020年度海洋科学技术奖二等奖(排名第四)

[3] 2020年度浙江省科学技术进步奖三等奖(排名第四)

[4] 2020年度宁波市科学技术进步奖三等奖(排名第四)

[5] 2019年度上海市科技进步二等奖(排名第九)

[6] 2018年度上海市浦东新区科技进步一等奖(排名第九)

 

联系方式

地址:上海市浦东新区沪城环路999

E-mail:x-liang@shou.edu.cn

 

 


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